Patent · US Active

FXR (NR1H4) modulating compounds

US9938278B2 · kind B2 · utility

9Cited by

3References

12Claims

0Family size

Assignee

Gilead Sciences, Inc. · US

Inventors

Christian Gege · Ehingen (Donau), DE
Claus Kremoser · Heidelberg, DE
Olaf Kinzel · Heidelberg, DE
Peter A. Blomgren · Issaquah, US
Kevin S. Currie · North Branford, US
Jeffrey E. Kropf · Branford, US
Aaron C. Schmitt · Hamden, US
William J. Watkins · Saratoga, US
Jianjun Xu · Bellevue, US

Key dates

Filing date	Dec 16, 2015
Grant date	Apr 10, 2018
Priority date	—
Expiry date	Apr 13, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.