Compositions and methods directed to treating liver fibrosis
US9944671B2 · kind B2 · utility
7Cited by
0References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 2, 2011 |
| Grant date | Apr 17, 2018 |
| Priority date | — |
| Expiry date | Jun 2, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the COL1A1, TGF-β, and SMAD2/3 genes, and methods of using such dsRNA compositions to inhibit expression of COL1A1, TGF-β, and SMAD2/3.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.