Patent · US Active

DNA polymerases with improved activity

US9951320B2 · kind B2 · utility

1Cited by

5References

18Claims

0Family size

Assignee

Roche Molecular Systems, Inc. · US

Inventors

Keith Bauer · Los Altos, US
Thomas W. Myers · Dublin, US
Shawn Suko · El Sobrante, US

Key dates

Filing date	Jul 28, 2016
Grant date	Apr 24, 2018
Priority date	—
Expiry date	Jul 28, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y207/07049
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.