Methods and compositions for treatment of a genetic condition

US9963715B2 · kind B2 · utility

Assignee

• Sangamo Therapeutics, Inc. · US

Inventors

• Gregory J. Cost · Berkeley, US
• Philip D. Gregory · Richmond, US
• Dmitry Guschin · Richmond, US
• Michael C. Holmes · Richmond, US
• Jeffrey C. Miller · Pleasanton, US
• David Paschon · Oakland, US
• Edward J. Rebar · Richmond, US
• Andreas Reik · Richmond, US
• Fyodor Urnov · Richmond, US
• Lei Zhang · Beijing, CN

Key dates

• Filing date: Aug 29, 2013
• Grant date: May 8, 2018
• Expiry date: May 12, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/81
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed herein are nucleases and methods of using these nucleases for alteration of a globin gene and generation of cells.