Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof
US9980947B2 · kind B2 · utility
10Cited by
28References
87Claims
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Assignee
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Key dates
| Filing date | Dec 17, 2015 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | Dec 21, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure:and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.