Patent · US Active

Preparation method for revaprazan hydrochloride

US9981917B2 · kind B2 · utility

0Cited by

4References

30Claims

0Family size

Assignee

JIANGSU TASLY DIYI PHARMACEUTICALS CO., LTD. · CN

Inventors

Wenzheng LIU · Lo Wu, CN
Guocheng Wang · 安丰镇, CN
Qingwei Hou · Tianjin, CN
Qiaoping Cui · 安丰镇, CN
Zhanyuan Zhu · 安丰镇, CN
Jinping Liu · Ballston Lake, US
Mingbo Yang · 安丰镇, CN
Hongguang Meng · 安丰镇, CN

Key dates

Filing date	Nov 12, 2015
Grant date	May 29, 2018
Priority date	—
Expiry date	Nov 12, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided is a preparation method for revaprazan hydrochloride, the method comprising: (1) the preparation of 4-hydroxyl-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (2) the preparation of 4-chloro-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (3) the preparation of revaprazan hydrochloride. The method has advantages such as simple operations, high product purity, good yield and suitability for industrial production.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.