Imidazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
US9981969B2 · kind B2 · utility
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12References
5Claims
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Key dates
| Filing date | Jun 2, 2014 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | Jun 2, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to Imidazole Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein A, B, Y, R1 and R2 are as defined herein. The present invention also relates to compositions comprising at least one Imidazole Derivative, and methods of using the Imidazole Derivatives for inhibiting CYP450 3A. Inhibition of CYP450 3A can be used to improve the pharmacokinetics of a drug that is metabolized by CYP450 3A4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.