Substituted 5-flouro-1H-pyrazolopyridines and their use

US9993476B2 · kind B2 · utility

Assignee

• Adverio Pharma GmbH · DE

Inventors

• Markus Follmann
• Johannes-Peter Stasch · Wuppertal, DE
• Gorden Redlich · Bochum, DE
• Jens Ackerstaff · Mülheim an der Ruhr, DE
• Nils Griebenow · Milford, US
• Walter Kroh · Wuppertal, DE
• Andreas Knorr · Erkrath, DE
• Eva-Maria Becker · Wuppertal, DE
• Frank Wunder · Wuppertal, DE
• Volkhart Min-Jian Li · Velbert, DE
• Elke Hartmann · Wuppertal, DE
• Joachim Mittendorf · Wuppertal, DE
• Karl-Heinz Schlemmer · Wuppertal, DE
• Rolf Jautelat · Haan, DE
• Donald Bierer · Daly City, US

Key dates

• Filing date: Nov 10, 2016
• Grant date: Jun 12, 2018
• Expiry date: Nov 10, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.