Patent · US Active

1′-substituted carba-nucleoside analogs for antiviral treatment

USRE46762E1 · kind E1 · reissue

27Cited by
32References
33Claims
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Key dates

Filing dateOct 7, 2016
Grant dateMar 27, 2018
Priority date
Expiry dateOct 7, 2036

Classification

  • Technology area (CPC —)General

Abstract

Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.