Broadly neutralizing antibody and uses thereof

USRE50268E1 · kind E1 · reissue

Assignees

• International AIDS Vaccine Initiative, Inc. · US
• THE SCRIPPS RESEARCH INSTITUTE · US
• Cornell University · IT

Inventors

• Dennis R. Burton · Village of La Jolla, US
• Marit J. Van Gils · Village of La Jolla, US
• Wayne Koff · Stony Brook, US
• Pascal Raymond Georges Poignard · San Diego, US
• Rogier W. Sanders · Ithaca, US
• Melissa Danielle De Jean De St. Marcel Simek-Lemos · Brooklyn, US
• Devin Sok · Village of La Jolla, US

Key dates

• Filing date: Apr 8, 2022
• Grant date: Jan 14, 2025
• Expiry date: Apr 8, 2042

Classification

• Technology area (CPC —): General

Abstract

The present invention relates to an exceptionally broad and potent neutralizing antibody which may comprise cross-clade neutralizing coverage of 83% at a median IC50 of 0.003 μg/ml, compositions containing the same and uses thereof.