Patent assignee · US · COMPANY

Adaptive Biotechnologies Corporation

55Patents
55Active
55Granted
55Portfolio score

Filing activity: Aug 28, 2012 → Jul 20, 2023

Most-cited patents

PatentTitleAreaCited byStatus
US9512487B2 Monitoring health and disease status using clonotype profiles Chemistry; Metallurgy 107 Active
US9506119B2 Method of sequence determination using sequence tags Chemistry; Metallurgy 80 Active
US10246752B2 Methods of monitoring conditions by sequence analysis Emerging Cross-Sectional Technologies 77 Active
US10221461B2 Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization Physics 45 Active
US9416420B2 Monitoring health and disease status using clonotype profiles Chemistry; Metallurgy 44 Active
US9150905B2 Compositions and method for measuring and calibrating amplification bias in multiplexed PCR reactions Chemistry; Metallurgy 44 Active
US9708657B2 Method for generating clonotype profiles using sequence tags Emerging Cross-Sectional Technologies 31 Active
US10077478B2 Determining paired immune receptor chains from frequency matched subunits Chemistry; Metallurgy 26 Active
US9371558B2 Compositions and method for measuring and calibrating amplification bias in multiplexed PCR reactions Chemistry; Metallurgy 22 Active
US9279159B2 Quantification of adaptive immune cell genomes in a complex mixture of cells Chemistry; Metallurgy 21 Active
US10066265B2 Determining antigen-specific t-cells Chemistry; Metallurgy 21 Active
US9394567B2 Detection and quantification of sample contamination in immune repertoire analysis Chemistry; Metallurgy 20 Active
US9181590B2 Quantification of adaptive immune cell genomes in a complex mixture of cells Chemistry; Metallurgy 17 Active
US10155992B2 Monitoring health and disease status using clonotype profiles Chemistry; Metallurgy 16 Active
US10077473B2 Method for genotyping clonotype profiles using sequence tags Emerging Cross-Sectional Technologies 13 Active
US10392663B2 Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples Chemistry; Metallurgy 10 Active
US10266901B2 Methods of monitoring conditions by sequence analysis Emerging Cross-Sectional Technologies 9 Active
US10150996B2 Quantification of adaptive immune cell genomes in a complex mixture of cells Chemistry; Metallurgy 9 Active
US9181591B2 Quantification of adaptive immune cell genomes in a complex mixture of cells Chemistry; Metallurgy 9 Active
US9365901B2 Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia Chemistry; Metallurgy 9 Active
US10428325B1 Identification of antigen-specific B cell receptors Chemistry; Metallurgy 8 Active
US9499865B2 Detection and measurement of tissue-infiltrating lymphocytes Physics 8 Active
US10214770B2 Compositions and method for measuring and calibrating amplification bias in multiplexed PCR reactions Chemistry; Metallurgy 7 Active
US10246701B2 Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture Chemistry; Metallurgy 6 Active
US10323276B2 Adaptive immunity profiling and methods for generation of monoclonal antibodies Chemistry; Metallurgy 5 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.