Inventor · Bethesda, MD, US

Brian R. Murphy

81Patents
15h-index
49Co-inventors
84Inventor score

Filing activity: Jun 18, 1975 → Jul 19, 2023

Most-cited inventions

PatentTitleAreaCited byStatus
US5922326A Attenuated respiratory syncytial virus vaccine compositions Chemistry; Metallurgy 55 Expired
US5762905A Human neutralizing monoclonal antibodies to respiratory syncytial virus Chemistry; Metallurgy 55 Expired
US3992522A Temperature-sensitive recombinant mutant viruses and a process for producing same Emerging Cross-Sectional Technologies 48 Expired
US4552758A Human use of avian-human reassortants as vaccines for influenza A virus Chemistry; Metallurgy 46 Expired
US6685942B1 Human neutralizing monoclonal antibodies to respiratory syncytial virus Emerging Cross-Sectional Technologies 45 Expired
US5993824A Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences Chemistry; Metallurgy 38 Expired
US7846455B2 Attenuated chimeric respiratory syncytial virus Chemistry; Metallurgy 29 Expired
US6713066B1 Production of attenuated respiratory syncytial virus vaccines involving modification of M2 ORF2 Chemistry; Metallurgy 25 Expired
US4683137A Temperature sensitive reassortant viruses and a vaccine against equine influenza Emerging Cross-Sectional Technologies 25 Expired
US6689367B1 Production of attenuated chimeric respiratory syncytial virus vaccines from cloned nucleotide sequences Chemistry; Metallurgy 24 Expired
US7488477B2 Neutralizing monoclonal antibodies to respiratory syncytial virus Chemistry; Metallurgy 23 Expired
US7208161B1 Production of attenuated parainfluenza virus vaccines from cloned nucleotide sequences Chemistry; Metallurgy 22 Expired
US7704509B2 Recovery of recombinant human parainfluenza virus type 1 (HPIV1) from cDNA and use of recombinant HPIV1 in immunogenic compositions and as vectors to elicit immune responses against PIV and other human pathogens Chemistry; Metallurgy 18 Expired
US7709007B2 Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences Chemistry; Metallurgy 15 Active
US8221759B2 Neutralizing monoclonal antibodies to respiratory syncytial virus Chemistry; Metallurgy 15 Active
US7192593B2 Use of recombinant parainfluenza viruses (PIVs) as vectors to protect against infection and disease caused by PIV and other human pathogens Chemistry; Metallurgy 14 Expired
US7517531B2 Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-UTR of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4 Emerging Cross-Sectional Technologies 13 Active
US7364737B2 Human neutralizing monoclonal antibodies to respiratory syncytial virus Emerging Cross-Sectional Technologies 13 Expired
US6410023B1 Recombinant parainfluenza virus vaccines attenuated by deletion or ablation of a non-essential gene Chemistry; Metallurgy 13 Expired
US7250171B1 Construction and use of recombinant parainfluenza viruses expressing a chimeric glycoprotein Chemistry; Metallurgy 13 Expired
US8075903B2 Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-UTR of dengue types 1, 2, 3, and 4 or antigenic chimeric dengue viruses 1, 2, 3, and 4 Emerging Cross-Sectional Technologies 12 Active
US7226602B2 Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses Emerging Cross-Sectional Technologies 11 Expired
US6923971B2 Respiratory syncytial virus vaccines expressing protective antigens from promoter-proximal genes Chemistry; Metallurgy 9 Expired
US7704491B2 Recombinant human metapneumovirus and its use Chemistry; Metallurgy 9 Expired
US8632782B2 Recombinant attenuated dengue viruses comprising mutations in NS5 and the 3′ untranslated region Emerging Cross-Sectional Technologies 9 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.