Patent · US Active

Syk inhibitors

US10005774B2 · kind B2 · utility

4Cited by
7References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 9, 2016
Grant dateJun 26, 2018
Priority date—
Expiry dateJun 11, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein X1, X2, X3, R2, R3, R4, R5, and Y are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.