Patent · US Active

Carbohydrate conjugated RNA agents and process for their preparation

US10086081B2 · kind B2 · utility

4Cited by

0References

10Claims

0Family size

Assignee

Alnylam Pharmaceuticals, Inc. · US

Inventors

Jayaprakash K. Nair · Cambridge, US
Alexander V. Kelin · Cambridge, US
Pachamuthu Kandasamy · Cambridge, US
Kallanthottathil G. Rajeev · Wayland, US
Muthiah Manoharan · Carlsbad, US

Key dates

Filing date	Aug 6, 2013
Grant date	Oct 2, 2018
Priority date	—
Expiry date	Jan 9, 2034

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This disclosure relates to an improved process for the preparation of carbohydrate conjugates. The disclosure also relates to carbohydrate conjugated iRNA agents comprising these carbohydrate conjugates, which have improved purity and are advantageous for the in vivo delivery of the iRNA agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.