[[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]- 1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties

US4791111A · kind A · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Jan Heeres · Vosselaar, BE
• Leo Jacobus Jozef Backx · Arendonk, BE
• Jozef Bertha August Thijssen · Kasterlee, BE
• Alfonsus G. Knaeps · Herentals, BE

Key dates

• Filing date: Oct 16, 1986
• Grant date: Dec 13, 1988
• Expiry date: Oct 16, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D249/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H -imidazoles and 1H-1,2,4-triazoles, having anti-microbial activity, compositions containing the same, and methods of inhibiting and/or eliminating the development of fungi and bacteria in warm-blooded animals suffering from diseases caused by these fungi and/or bacteria.