Prodrugs for oxadiazole muscarinic agonists
US5242927A · kind A · utility
17Cited by
7References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 18, 1988 |
| Grant date | Sep 7, 1993 |
| Priority date | — |
| Expiry date | Jul 18, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A class of novel oxadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring and on the other ring carbon atom with a substituent which is convertible in vivo to an amino group, are potent muscarinic agonists, and exhibit improved CNS penetrability and duration of action compared with the corresponding amino compounds. The compounds are therefore useful in the treatment of neurological and mental illnesses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.