Patent · US Expired

Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription

US5322770A · kind A · utility

294Cited by
2References
18Claims
0Family size

Assignee

Inventor

Key dates

Filing dateDec 22, 1989
Grant dateJun 21, 1994
Priority date
Expiry dateDec 22, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/686
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Methods are provided for the replication and amplification of RNA sequences by thermostable DNA polymerases. Reverse transcription of RNA is catalyzed by, for example, 92 kDa Taq, 64 kDa Taq, and Tth DNA polymerase. Reverse transcription is coupled to PCR amplification in a one enzyme procedure using a thermostable polymerase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.