David H. Gelfand
67Patents
35h-index
50Co-inventors
91Inventor score
Filing activity: Feb 17, 1983 → Jul 6, 2017
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US4965188A | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme | Chemistry; Metallurgy | 2,086 | Expired |
| US5210015A | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase | Emerging Cross-Sectional Technologies | 871 | Expired |
| US4889818A | Purified thermostable enzyme | Chemistry; Metallurgy | 591 | Expired |
| US5487972A | Nucleic acid detection by the 5'-3'exonuclease activity of polymerases acting on adjacently hybridized oligonucleotides | Emerging Cross-Sectional Technologies | 349 | Expired |
| US5322770A | Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription | Chemistry; Metallurgy | 294 | Expired |
| US5418149A | Reduction of non-specific amplification glycosylase using DUTP and DNA uracil | Chemistry; Metallurgy | 280 | Expired |
| US5804375A | Reaction mixtures for detection of target nucleic acids | Emerging Cross-Sectional Technologies | 259 | Expired |
| US5079352A | Purified thermostable enzyme | Chemistry; Metallurgy | 252 | Expired |
| US5310652A | Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription | Chemistry; Metallurgy | 215 | Expired |
| US5618711A | Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase | Chemistry; Metallurgy | 188 | Expired |
| US5075216A | Methods for DNA sequencing with thermus aquaticus DNA polymerase | Emerging Cross-Sectional Technologies | 159 | Expired |
| US5374553A | DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima | Chemistry; Metallurgy | 150 | Expired |
| US6127155A | Stabilized thermostable nucleic acid polymerase compositions containing non-ionic polymeric detergents | Emerging Cross-Sectional Technologies | 114 | Expired |
| US5466591A | 5' to 3' exonuclease mutations of thermostable DNA polymerases | Chemistry; Metallurgy | 113 | Expired |
| US5674738A | DNA encoding thermostable nucleic acid polymerase enzyme from thermus species Z05 | Chemistry; Metallurgy | 100 | Expired |
| US6040166A | Kits for amplifying and detecting nucleic acid sequences, including a probe | Emerging Cross-Sectional Technologies | 95 | Expired |
| US5407800A | Reverse transcription with Thermus thermophilus polymerase | Chemistry; Metallurgy | 91 | Expired |
| US5561058A | Methods for coupled high temperatures reverse transcription and polymerase chain reactions | Chemistry; Metallurgy | 84 | Expired |
| US6214979A | Homogeneous assay system | Emerging Cross-Sectional Technologies | 79 | Expired |
| US6197563A | Kits for amplifying and detecting nucleic acid sequences | Chemistry; Metallurgy | 77 | Expired |
| US5455170A | Mutated thermostable nucleic acid polymerase enzyme from Thermus species Z05 | Chemistry; Metallurgy | 70 | Expired |
| US5789224A | Recombinant expression vectors and purification methods for thermus thermophilus DNA polymerase | Chemistry; Metallurgy | 69 | Expired |
| US5641864A | Kits for high temperature reverse transcription of RNA | Chemistry; Metallurgy | 66 | Expired |
| US5352600A | Purified thermostable enzyme | Chemistry; Metallurgy | 65 | Expired |
| US5693517A | Reagents and methods for coupled high temperature reverse transcription and polymerase chain reactions | Emerging Cross-Sectional Technologies | 63 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.