Thiadiazoles useful in the treatment of senile dementia
US5405853A · kind A · utility
14Cited by
4References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 13, 1993 |
| Grant date | Apr 11, 1995 |
| Priority date | — |
| Expiry date | Dec 13, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A class of novel thiadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring system, and substituted on the other ring carbon atom with a substituent of low lipophilicity, or a hydrocarbon substituent; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses, and are also of benefit in the treatment of severe painful conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.