Patent · US Expired

Thiol-derivatized nucleosides

US5578718A · kind A · utility

341Cited by
3References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 3, 1993
Grant dateNov 26, 1996
Priority date
Expiry dateSep 3, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/3533
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Nucleosides and linked nucleosides functionalized to include alkylthiol chemical functionality at ribofuranosyl positions, nucleosidic base positions, or on internucleoside linkages. In certain embodiments, the compounds of the invention further include steroids, reporter molecules, reporter enzymes, lipophilic molecules, peptides or proteins attached to the nucleosides through the alkylthio group.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.