2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes)
US5716824A · kind A · utility
118Cited by
5References
12Claims
0Family size
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Key dates
| Filing date | Apr 20, 1995 |
| Grant date | Feb 10, 1998 |
| Priority date | — |
| Expiry date | Apr 20, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound having the formula: ##STR1## wherein, R1 represents 2'-O-R.sub.3 -thio-R.sub.3 and/or 2'-C-R.sub.3 -thio-R.sub.3, wherein R.sub.3 is independently a moiety selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester, X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.