Sulfuric acid esters of amino sugars

US5767268A · kind A · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Alexander Chucholowski · San Diego, US
• Jurgen Fingerle · Rheinfelden (Baden), DE
• Niggi Iberg · Basel, CH
• Hans-Peter Marki · Basel, CH
• Rita Muller · Basel, CH
• Michael Pech · Hartheim, DE
• Marianne Rouge · Basel, CH
• Gerard Schmid · Kienberg, CH
• Thomas B. Tschopp · Ettingen, CH
• Hans Peter Wessel · Heitersheim, DE

Key dates

• Filing date: Apr 26, 1996
• Grant date: Jun 16, 1998
• Expiry date: Apr 26, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H15/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of formulas ##STR1## wherein, B is lower alkylene or an optionally substituted aromatic ring system; PA1 G.sup.1, G.sup.2 and G.sup.3 each independently signify a residue of a glycopyranoside, a glycopyranose or a derivative thereof, with at least one hydroxy group of residue G.sup.1, G.sup.2 or G.sup.3 being esterified with sulfuric acid, and pharmaceutically usable salts thereof, are useful for the treatment of disorders which are characterized by excessive or destructive proliferation of smooth muscle cells.