Amino and peptido modified enzymatic nucleic acid
US5783425A · kind A · utility
17Cited by
2References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 16, 1994 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Dec 16, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3535
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An enzymatic nucleic acid molecule, comprising a moiety having the formula: ##STR1## wherein B is a nucleotide base or hydrogen; R is selected from the group consisting of aminoacyl group, and NHR.sub.4 group, wherein said R.sub.4 is independently selected from the group consisting of a peptidyl group containing between 2 and 5 amino acids inclusive, and CO--CR.sub.1 R.sub.2 R.sub.3, wherein R.sub.1, R.sub.2 and R.sub.3 independently is selected from the group consisting of hydrogen, an alkyl group containing between 2 and 10 carbon atoms inclusive, and an alkyl amine; and the zigzag lines are independently hydrogen or a bond.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.