Patent · US Expired

2'-O-alkylthioalkyl and 2'-C-alkylthioalkyl-containing nucleic acids

US5840876A · kind A · utility

12Cited by
9References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 12, 1997
Grant dateNov 24, 1998
Priority date
Expiry dateJun 12, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/346
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound having the formula: ##STR1## wherein, R1 represents 2'-O-R.sub.3 -thio-R.sub.3 and/or 2'-C-R.sub.3 -thio-R.sub.3, wherein R.sub.3 is independently a compound selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester; X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.