Itraconazole and stereoisomers

US5998413A · kind A · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Jan Heeres · Vosselaar, BE
• Jean Mesens · Wechelderzande, BE
• Jozef Peeters · Ieper, BE

Key dates

• Filing date: Jul 9, 1996
• Grant date: Dec 7, 1999
• Expiry date: Jul 9, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/56
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Anti-infective compositions for the treatment of a human in need of therapy for a systemic or topical fungal infection which comprise a pharmaceutically acceptable carrier and a therapeutically effective amount of (2R,4S) itraconazole or a pharmaceutically acceptable salt thereof, substantially free of its (2S,4R) stereoisomer.