Inhibitors of human plasmin derived from the kunitz domains
US6010880A · kind A · utility
45Cited by
3References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 7, 1997 |
| Grant date | Jan 4, 2000 |
| Priority date | — |
| Expiry date | Jan 7, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/8114
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel mutants of the first Kunitz domain (K.sub.1) of the human lipoprotein-associated coagulation inhibitor (LACI) which inhibit plasmin. The invention also relates to other modified Kunitz domains that inhibit plasmin and to other plasmin inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.