Patent · US Expired

Antisense inhibition of focal adhesion kinase expression

US6133031A · kind A · utility

38Cited by
1References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 19, 1999
Grant dateOct 17, 2000
Priority date
Expiry dateAug 19, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/346
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds, compositions and methods are provided for inhibiting FAK mediated signaling. The compositions comprise antisense compounds targeted to nucleic acids encoding FAK. Methods of using these antisense compounds for inhibition of FAK expression and for treatment of diseases, particularly cancers, associated with overexpression or constitutive activation of FAK are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.