Brett P. Monia
148Patents
35h-index
75Co-inventors
93Inventor score
Filing activity: Dec 14, 1992 → Apr 15, 2021
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5623065A | Gapped 2' modified oligonucleotides | Chemistry; Metallurgy | 319 | Expired |
| US6210892A | Alteration of cellular behavior by antisense modulation of mRNA processing | Emerging Cross-Sectional Technologies | 245 | Expired |
| US6451991B1 | Sugar-modified gapped oligonucleotides | Human Necessities | 228 | Expired |
| US6172216A | Antisense modulation of BCL-X expression | Chemistry; Metallurgy | 215 | Expired |
| US7015315B1 | Gapped oligonucleotides | Chemistry; Metallurgy | 194 | Expired |
| US6133246A | Antisense oligonucleotide compositions and methods for the modulation of JNK proteins | Chemistry; Metallurgy | 140 | Expired |
| US7148204B2 | Antisense modulation of bcl-x expression | Chemistry; Metallurgy | 138 | Expired |
| US7732590B2 | Modulation of diacylglycerol acyltransferase 2 expression | Chemistry; Metallurgy | 129 | Expired |
| US7709630B2 | Antisense modulation of connective tissue growth factor expression | Emerging Cross-Sectional Technologies | 123 | Active |
| US6100090A | Antisense inhibition of PI3K p85 expression | Emerging Cross-Sectional Technologies | 111 | Expired |
| US6287860A | Antisense inhibition of MEKK2 expression | Emerging Cross-Sectional Technologies | 103 | Expired |
| US5576208A | Antisense oligonucleotide inhibition of the RAS gene | Chemistry; Metallurgy | 102 | Expired |
| US6524854B1 | Antisense inhibition of PKA regulatory subunit RII alpha expression | Emerging Cross-Sectional Technologies | 91 | Expired |
| US5958773A | Antisense modulation of AKT-1 expression | Emerging Cross-Sectional Technologies | 87 | Expired |
| US6326199A | Gapped 2' modified oligonucleotides | Chemistry; Metallurgy | 75 | Expired |
| US5955589A | Gapped 2' modified oligonucleotides | Chemistry; Metallurgy | 73 | Expired |
| US6033910A | Antisense inhibition of MAP kinase kinase 6 expression | Emerging Cross-Sectional Technologies | 70 | Expired |
| US6391636B1 | Antisense oligonucleotide modulation of raf gene expression | Chemistry; Metallurgy | 64 | Expired |
| US6383808B1 | Antisense inhibition of clusterin expression | Emerging Cross-Sectional Technologies | 62 | Expired |
| US5582986A | Antisense oligonucleotide inhibition of the ras gene | Chemistry; Metallurgy | 54 | Expired |
| US6146829A | Gapped 2' modified oligonucleotides | Chemistry; Metallurgy | 53 | Expired |
| US6046049A | Antisense modulation of PI3 kinase p110 delta expression | Emerging Cross-Sectional Technologies | 53 | Expired |
| US5656612A | Antisense oligonucleotide modulation of raf gene expression | Chemistry; Metallurgy | 52 | Expired |
| US6214986A | Antisense modulation of bcl-x expression | Chemistry; Metallurgy | 50 | Expired |
| US6184212A | Antisense modulation of human mdm2 expression | Emerging Cross-Sectional Technologies | 48 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.