Patent · US Expired

Antisense modulation of human mdm2 expression

US6184212A · kind A · utility

48Cited by
3References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 26, 1999
Grant dateFeb 6, 2001
Priority date
Expiry dateMar 26, 2019

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/582
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds, compositions and methods are provided for inhibiting the expression of human mdm2. The compositions include antisense compounds targeted to nucleic acids encoding mdm2. Methods of using these oligonucleotides for inhibition of mdm2 expression and for treatment of diseases such as cancers associated with overexpression of mdm2 are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.