Patent · US Expired

2'-O-alkylthioalkyl and 2'-c-alkylthioalkyl-containing nucleic acids

US6239272A · kind A · utility

25Cited by
10References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 17, 1998
Grant dateMay 29, 2001
Priority date
Expiry dateJun 17, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/346
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound having the formula: ##STR1## wherein, R1 represents 2'-O-R.sub.3 -thio-R.sub.3 and/or 2'-C-R.sub.3 -thio-R.sub.3, wherein R.sub.3 is a compound independently selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester, X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.