N-(4-carbamimidoyl-phenyl)-glycine derivatives

US6242644A · kind A · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Jean Ackermann · Riehen, CH
• Leo Alig · Kaiseraugst, CH
• Alexander Chucholowski · San Diego, US
• Katrin Groebke · Basel, CH
• Kurt Hilpert · Therwil, CH
• Holger Kuehne · Soest, DE
• Ulrike Obst · Weil am Rhein, DE
• Lutz Weber · Weil am Rhein, DE
• Hans Peter Wessel · Heitersheim, DE

Key dates

• Filing date: Dec 14, 1999
• Grant date: Jun 5, 2001
• Expiry date: Dec 14, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: ##STR1## wherein R.sup.1, E, X.sup.1 to X.sup.4 and G.sup.1 and G.sup.2 are as defined in the description and the claims, as well as hydrates or solvates and physiologically usable salts thereof.