Patent · US Expired

Pyrrolidine modulators of chemokine receptor activity

US6265434A · kind A · utility

7Cited by
3References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 4, 2000
Grant dateJul 24, 2001
Priority date
Expiry dateApr 4, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to pyrrolidine compounds of the formula 1: ##STR1## (wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.