Targeted oligonucleotide conjugates
US6300319A · kind A · utility
180Cited by
24References
25Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 16, 1998 |
| Grant date | Oct 9, 2001 |
| Priority date | — |
| Expiry date | Jun 16, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/87
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides improved ingress of therapeutic and other moieties into cellular targets. In accordance with preferred embodiments, complexes are provided which carry primary moieties, chiefly therapeutic moieties, to such target cells. Such complexes preferably feature cell surface receptor ligands to provide specificity. Such ligands are preferably bound to primary moieties through polyfunctional manifold compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.