Patent · US Expired

Itraconazole and saperconazole stereoisomers

US6346518B1 · kind B1 · utility

3Cited by

9References

14Claims

0Family size

Assignee

Janssen Pharmaceutica NA · BE

Inventors

Jan Heeres · Vosselaar, BE
Jean Mesens · Wechelderzande, BE
Jozef Peeters · Ieper, BE

Key dates

Filing date	Jan 26, 1995
Grant date	Feb 12, 2002
Priority date	—
Expiry date	Jan 26, 2015

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/724
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is concerned with the stereoisomeric forms of itraconazole (X=Cl) and saperconazole (X=F), which may be represented by the formula and the pharmaceutically acceptable acid addition salt forms thereof, processes for preparing said stereoisomeric forms, the complexes thereof with cyclodextrin derivatives, pharmaceutical compositions comprising said complexes and methods of preparing said complexes and pharmaceutical compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.