Antisense oligonucleotide modulation of raf gene expression
US6391636B1 · kind B1 · utility
64Cited by
9References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 1, 2000 |
| Grant date | May 21, 2002 |
| Priority date | — |
| Expiry date | Mar 1, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3517
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Oligonucleotides are provided which are targeted to nucleic acids encoding human raf and capable of inhibiting raf expression. Methods of inhibiting the expression of human raf using oligonucleotides of the invention are also provided. The present invention further comprises methods of preventing or inhibiting hyperproliferation of cells and methods of treating abnormal proliferative conditions which employ oligonucleotides of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.