Oligonucleotides having alkylphosphonate linkages and methods for their preparation
US6486313B1 · kind B1 · utility
1Cited by
3References
16Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Feb 18, 1999 |
| Grant date | Nov 26, 2002 |
| Priority date | — |
| Expiry date | Feb 18, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides alkylphosphonate dimers and oligonucleotides prepared therefrom. The invention further provides novel methods for the preparation of these alkylphosphonate dimers. Methods for the preparation of substantially diastereomerically pure alkylphosphonate dimers are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.