Synthetic ribonucleic acids with RNAse activity
US6528640B1 · kind B1 · utility
47Cited by
1References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 1999 |
| Grant date | Mar 4, 2003 |
| Priority date | — |
| Expiry date | Dec 29, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel nucleotide triphosphates, methods of synthesis and process of incorporating these nucleotide triphosphates into oligonucleotides, and isolation of novel nucleic acid catalysts (e.g., ribozymes) are disclosed. Also, described are the use of novel enzymatic nucleic acid molecules to inhibit HER2/neu/ErbB2 gene expression and their applications in human therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.