Enzymatic nucleic acids containing 5′-and or 3′-cap structures

US6586238B1 · kind B1 · utility

Assignee

• Ribozyme Pharmaceuticals, Inc. · US

Inventors

• Jasenka Matulic-Adamic · Boulder, US
• Leonid Beigelman · San Mateo, US
• Alexander Karpeisky · Aurora, US
• Thale Jarvis · Boulder, US
• Nassim Usman · Boston, US
• Anthony DiRenzo · Boulder, US
• Francine Wincott · Longmont, US

Key dates

• Filing date: Oct 15, 1999
• Grant date: Jul 1, 2003
• Expiry date: Oct 15, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/121
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

An enzymatic nucleic acid molecule comprising a 5′- and/or a 3′-cap structure, wherein said structure is not a 5′-5′-linked inverted nucleotide or a 3′-3′-linked inverted nucleotide.