Benzodioxole derivatives

US6900227B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Alexander Alanine · Basel, CH
• Konrad Bleicher · Glückstadt, DE
• Wolfgang Guba · Memmingen, DE
• Wolfgang Haap · Bad Kötzting, DE
• Dagmar Kube · Rochester, US
• Thomas Luebbers · Soest, DE
• Jean-Marc Plancher · Rixheim, FR
• Olivier Roche · Folgensbourg, FR
• Mark Rogers-Evans · Bottmingen, CH
• Gisbert Schneider · Zürich, CH
• Jochen Zuegge · Frankfurt, DE

Key dates

• Filing date: Jul 24, 2003
• Grant date: May 31, 2005
• Expiry date: Jul 24, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of the general formula and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases such as obesity by selective modulation of CB1 receptors.