Antisense modulation of bcl-x expression
US7148204B2 · kind B2 · utility
138Cited by
11References
16Claims
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Key dates
| Filing date | Nov 21, 2002 |
| Grant date | Dec 12, 2006 |
| Priority date | — |
| Expiry date | Dec 7, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are provided for modulating the expression of bcl-x. Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding bcl-x are preferred. Methods of using these compounds for modulation of bcl-x expression and for treatment of diseases associated with expression of bcl-x are also provided. Methods of sensitizing cells to apoptotic stimuli are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.