Pyridazine derivatives as ligands for GABA receptors
US7381725B2 · kind B2 · utility
12Cited by
10References
4Claims
0Family size
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Key dates
| Filing date | Aug 4, 2003 |
| Grant date | Jun 3, 2008 |
| Priority date | — |
| Expiry date | May 13, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A class of pyridazine derivatives, substituted in the 4-position by an optionally substituted heteroaromatic ring, being selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 and/or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.