Patent · US Expired

Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-2pyrimidinyl]amino]benzonitrile

US7399856B2 · kind B2 · utility

13Cited by

0References

12Claims

0Family size

Assignee

Janssen Pharmaceutica NA · BE

Inventors

Didier Schils · Loupoigne, BE
Joannes Josephus Maria Willems · Oud-Turnhout, BE
Bart Petrus Anna Maria Jozef Medaer · Lille, BE
Elisabeth Therese Jeanne Pasquier · Le Neubourg, FR
Paul Adriaan Jan Janssen · Vosselaar, BE
Jan Heeres · Vosselaar, BE
Ruben Gerardus George Leenders · Nijmegen, NL
Jérôme Emile Georges Guillemont · Andé, FR

Key dates

Filing date	Aug 7, 2003
Grant date	Jul 15, 2008
Priority date	—
Expiry date	Aug 7, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C253/30
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]amino]benzonitrile of formula (I), a N-oxide, a pharmaceutically acceptable acid addition salt, a quaternary amine or a stereochemically isomeric form thereof are provided, said processes comprise:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.