Dihydroxyphenyl isoindolymethanones
US7754725B2 · kind B2 · utility
12Cited by
7References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 1, 2007 |
| Grant date | Jul 13, 2010 |
| Priority date | — |
| Expiry date | Apr 26, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds having the formula (I):and in particular, those of subgenus VIIaare disclosed as inhibits or modulators of the activity of the heat shock protein Hsp90. As such they are useful for treating cancer, particularly hematopoietic tumors of lymphoid or myeloid lineage, prostate cancer, lung cancer, gastrointestinal stromal tumor, breast cancer and melanoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.