Patent · US Active

Thiazole and pyrazole derivatives as Flt-3 kinase inhibitors

US7795288B2 · kind B2 · utility

3Cited by
4References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 12, 2004
Grant dateSep 14, 2010
Priority date
Expiry dateMay 10, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to thiazole and pyrazole derivatives of formula (I) wherein Q is S and X is C, or Q is CH and X is N; R1 is unsubstituted or substituted phenyl; and R2 is unsubstituted or substituted aryl or heteroaryl; or a salt of the said compounds, and to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives and to the use of such derivatives for the preparation of pharmaceutical compositions for the treatment especially of a proliferative disease, such as a tumour disease, in particular such diseases which respond to an inhibition of the Flt-3 kinase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.