Patent · US Active

Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds

US8389697B2 · kind B2 · utility

26Cited by

10References

15Claims

0Family size

Assignee

Genentech, Inc. · US

Inventors

Italo Beria · Nerviano, IT
Michele Caruso · Milano, IT
John A. Flygare · Burlingame, US
Vittoria Lupi · Milano, IT
Rita Perego · Milano, IT
Paul Polakis · Mill Valley, US
Andrew Polson · San Francisco, US
Matteo Salsa · Novara, IT
Susan D. Spencer · Tiburon, US
Barbara Valsasina · Milano, IT

Key dates

Filing date	Jan 27, 2012
Grant date	Mar 5, 2013
Priority date	—
Expiry date	Jan 27, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/76
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.