Therapeutic combinations of hydroxybenzamide derivatives as inhibitors of HSP90
US8530469B2 · kind B2 · utility
6Cited by
13References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 2011 |
| Grant date | Sep 10, 2013 |
| Priority date | — |
| Expiry date | Nov 12, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides a combination comprising an Hsp90 inhibitor compound of the formula (VII):or tautomer or salt thereof and one or more therapeutic agents selected from topoisomerase I inhibitors; antimetabolites; tubulin targeting agents; DNA binder and topoisomerase II inhibitors; alkylating agents; monoclonal antibodies; anti-hormones; signal transduction inhibitors; proteasome inhibitors; DNA methyl transferases; cytokines; retinoids and HDAC or HAT modulators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.