Amino azaheterocyclic carboxamides

US8637532B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Amanda E. Sutton · Hingham, US
• Ruoxi Lan · Waltham, US
• Thomas E. Richardson · Durham, US
• David Perrey · Durham, US
• Harold George Vandeveer · Indianapolis, US
• Bayard R. Huck · Sudbury, US
• Srinivasa Karra · Pembroke, US
• Xiaoling Chen · Sharon, US
• Yufang Xiao · Lexington, US
• Lesley Liu-Bujalski · Bedford, US
• Andreas Goutopoulos · Boston, US
• Frank Stieber · Heidelberg, DE
• Brian L. Hodous · Cambridge, US
• Hui Qiu · Lexington, US
• Reinaldo Jones · Lowell, US
• Brian H. Heasley · Wake Forest, US

Key dates

• Filing date: Feb 4, 2010
• Grant date: Jan 28, 2014
• Expiry date: Feb 4, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides novel substituted amino azaheterocyclic carboxamide compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.