Patent · US Active

Diagnosis and treatment of disease

US8697860B1 · kind B1 · utility

12Cited by

226References

16Claims

0Family size

Assignee

Isis Pharmaceuticals, Inc. · US

Inventors

Brett P. Monia · Carlsbad, US
Susan M. Freier · San Diego, US
Andrew M. Siwkowski · Carlsbad, US
Shuling Guo · Carlsbad, US

Key dates

Filing date	Jul 17, 2013
Grant date	Apr 15, 2014
Priority date	—
Expiry date	Jul 17, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.