Compositions, systems, and methods for immiscible fluid discrete volume manipulation

US9152150B1 · kind B1 · utility

Assignee

• Applied Biosystems, LLC · US

Inventors

• Linda G. Lee · Palo Alto, US
• Mark F. Oldham · Los Gatos, US
• Sam Woo · Redwood City, US
• David M. Cox · Gloucester, GB
• Richard T. Reel · Hayward, US
• Peter Ma · Cupertino, US
• Ben F. Johnson · Palo Alto, US
• Dennis Letho · Santa Clara, US

Key dates

• Filing date: Feb 22, 2008
• Grant date: Oct 6, 2015
• Expiry date: Jul 24, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/6439
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Systems and methods of manipulating discrete volumes of a first fluid in a second fluid are provided. In some embodiments, discrete volumes can be formed in a conduit. In other embodiments, addition fluid can be added to a discrete volume in a first conduit by injecting the addition fluid at a relatively higher pressure. In some embodiments, discrete volumes that normally would not coalesce can be manipulated to be merged together.