Trifluoromethyl-substituted fused pyrimidines and their use

US9266871B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Markus Follmann
• Johannes-Peter Stasch · Wuppertal, DE
• Gorden Redlich · Bochum, DE
• Dieter Lang · Velbert, DE
• Alexandros Vakalopoulos · Hilden, DE
• Frank Wunder · Wuppertal, DE
• Adrian Tersteegen · Wuppertal, DE

Key dates

• Filing date: Feb 28, 2014
• Grant date: Feb 23, 2016
• Expiry date: Feb 28, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel trifluoromethyl-substituted fused pyrimidines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.